Chemistry Department Faculty

Department of Chemistry
221 Science Center
State University of New York at Fredonia
Fredonia, NY 14063
Dr. Matthew A. Fountain
Professor of Chemistry and Biology 
Biochemistry Program Coordinator 
311 Science Center
Fredonia State University of New York
Fredonia, NY 14063 
Tel: (716) 673-3287 
Fax: (716) 673 3347





Biochemistry Lab   Images of student's lysozyme crystals

Advanced Biochemistry Examples of student protein posters (converted to PDF so some of the fonts have changed) Ef-Tu protein, Rhodopsin, Nop56/58:Fibrillarin complex in Box C/D RNPs



Structure determination of RNA and DNA structures using NMR and molecular modeling. Binidng of metal ions and metal containing ligands to DNA and RNA

Recent Publications




Selective Binding of Zn2+ Complexes to Human Telomeric G-Quadruplex DNA, Kevin E. Siters, Matthew A. Fountain*, and Janet R. Morrow, Inorg. Chem., 2014, 53 (21), pp 11540–11551


NMr structure Thymidine Tbulge wtih ligand


del Mundo IM, Siters KE, Fountain MA, Morrow JR. "Structural basis for bifunctional zinc(II) macrocyclic complex recognition of thymine bulges in DNA." Inorg Chem. 2012 May 7;51(9):5444-57.


Model of Zn(1) interaction with extrahelical thymine bulge.

delMundo, I. M.; Fountain, M. A.; Morrow, J. R. “Recognition of Thymine in DNA Bulges by a Zn(II) Macrocyclic Complex”, Chem. Comm. 2011, 47,8566-8568

 Parkesh R, Fountain M, Disney M.D. ”NMR spectroscopy and molecular dynamics simulation of r(CCGCUGCGG)₂reveal a dynamic UU internal loop found in myotonic dystrophy type 1”, Biochemistry. 2011, 50(5), 599-601.


Graphical abstract: Synthesis and luminescence properties of a trinucleotide–europium(III) complex conjugate

Escudier, J. M.; Dupouy, C.; Fountain, M. A.; Del Mundo I. M. A.; Jacklin, E. M.; Morrow, J. R.  “Synthesis and Luminescence Properties of a Trinucleotide Europium(III) Complex Conjugate”, Org. Biomolec. Chem. 2009, 7, 3251-3257. 



Page modified 6/5/15