Chemistry Department Faculty


Department of Chemistry
221 Science Center
SUNY Fredonia
Fredonia, NY 14063
(716)-673-3281

Dr. Fountain Dr. Matthew A. Fountain
Assistant Professor of Chemistry and Biology
Biochemistry Program Coordinator
204 Houghton Hall
SUNY College at Fredonia
Fredonia, NY 14063
Tel: (716) 673-3287
Fax: (716) 673 3347
Matthew.Fountain@Fredonia.edu

 

Courses

Biochemistry

Biochemistry Lab   Images of student's lysozyme crystals

Advanced Biochemistry Examples of student protein posters (converted to PDF so some of the fonts have changed) Ef-Tu protein, Rhodopsin, Nop56/58:Fibrillarin complex in Box C/D RNPs

 

Research

Structure determination of RNA and DNA structures using NMR and molecular modeling. Binidng of metal ions and metal containing ligands to DNA and RNA

Recent Publications

NMr structure Thymidine Tbulge wtih ligand

 

del Mundo IM, Siters KE, Fountain MA, Morrow JR. "Structural basis for bifunctional zinc(II) macrocyclic complex recognition of thymine bulges in DNA." Inorg Chem. 2012 May 7;51(9):5444-57.

 

Model of Zn(1) interaction with extrahelical thymine bulge.

delMundo, I. M.; Fountain, M. A.; Morrow, J. R. “Recognition of Thymine in DNA Bulges by a Zn(II) Macrocyclic Complex”, Chem. Comm. 2011, 47,8566-8568

 

http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/2011/bichaw.2011.50.issue-5/bi101896j/production/images/medium/bi-2010-01896j_0001.gif http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/2011/bichaw.2011.50.issue-5/bi101896j/production/images/large/bi-2010-01896j_0002.jpeg

 Parkesh R, Fountain M, Disney M.D. ”NMR spectroscopy and molecular dynamics simulation of r(CCGCUGCGG)₂reveal a dynamic UU internal loop found in myotonic dystrophy type 1”, Biochemistry. 2011, 50(5), 599-601.

 

Graphical abstract: Synthesis and luminescence properties of a trinucleotide–europium(III) complex conjugate

Escudier, J. M.; Dupouy, C.; Fountain, M. A.; Del Mundo I. M. A.; Jacklin, E. M.; Morrow, J. R.  “Synthesis and Luminescence Properties of a Trinucleotide Europium(III) Complex Conjugate”, Org. Biomolec. Chem. 2009, 7, 3251-3257. 

 

 


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