Natural Science Advisory Council
Michael A. Marletta

  Michael Marletta

Michael A. Marletta


 

Graduation date from Fredonia: 1973
Major(s) while at Fredonia:

Biology, Chemistry

Other Education

1978 Ph.D. University of California, San Francisco, CA

1978-80  Post-Doctoral training, Massachusetts Institute of Technology

Present professional positions

President-elect:

Professor and Chair of Chemistry and, Aldo DeBenedictis Distinguished Professor of Chemistry:

Professor of Biochemistry and Molecular Biology:

Professor of Cellular and Molecular Pharmacology:


Faculty Scientist:


Co-Director:

Scripps Research Institute, La Jolla, California

Department of Chemistry, University of California, Berkeley



Department of Molecular and Cell Biology, University of California, Berkeley

Department of Cellular and Molecular Pharmacology, University of California, San Francisco

Division of Physical Biosciences, Lawrence Berkeley National Laboratory

Chemical Biology Graduate Program, University of California, Berkeley

Office Phone/Fax:  510-666-2763
E-mail: marletta@berkeley.edu
Marletta Web Page

Past professional positions
Positions (academic)
2000

Miller Visiting Research Professor, Department of Chemistry, University of California, Berkeley

1998

Visiting Scientist, Brandeis University

1997-1998 Visiting Research Scientist, Biophysics Research Division, University of Michigan
1997-2001 Investigator, Howard Hughes Medical Institute
1991-2001

John G. Searle Professor of Medicinal Chemistry, College of Pharmacy, University of Michigan

Professor of Medicinal Chemistry, College of Pharmacy, University of Michigan

Professor of Biological Chemistry, Medical School, University of Michigan

1989-1991

Associate Professor of Biological Chemistry, Medical School, University of Michigan

1987-1991

Associate Professor of Medicinal Chemistry, College of Pharmacy, University of Michigan

1980-1987

Assistant  and Associate Professor of Toxicology, Department of Applied Biological Sciences, Massachusetts Institute of Technology

 
Professional affiliation(s), e.g. Boards, National Committees, etc.
 

National Academy of Sciences

 

American Association for the Advancement of Science

    

American Society for Biochemistry and Molecular Biology

 

American Chemical Society, Divisional Affiliation in Biological Chemistry and Medicinal Chemistry

 

The Nitric Oxide Society

  Institute of Medicine
 

American Academy of Arts and Sciences

Brief bio

Michael A. Marletta was born in Rochester New York on February 12, 1951.  After an A.B. in biology and chemistry (SUNY, College at Fredonia, 1973), PhD (University of California, San Francisco, 1978) with Prof. George L. Kenyon, and postdoctoral fellowship at MIT (1978-80) with Christopher T. Walsh, he joined the faculty at M.I.T. as an Assistant Professor of Toxicology in the Department of Applied Biological Sciences (1980-86).  He was promoted to Associate Professor in 1986.  In 1987 he moved to the University of Michigan as Associate Professor of Medicinal Chemistry, College of Pharmacy and Associate Professor of Biological Chemistry, Medical School.  He was promoted to Professor (1991) and appointed the John G. Searle Professor of Medicinal Chemistry.  In 1997 he was named to the Howard Hughes Medical Institute.  Marletta moved to the University of California, Berkeley in 2001 as Professor of Chemistry, and Professor of Biochemistry and Molecular Biology and Professor of Cellular and Molecular Pharmacology, UCSF and Faculty Scientist at the Lawrence Berkeley National Lab.  He was appointed the Aldo DeBenedictis Distinguished Professor of Chemistry in 2002.  On 1 July 2005, he became Chair of the Department of Chemistry at Berkeley. 

Awards he has received include: Burroughs Wellcome Fund George H. Hitchings Award for Innovative Methods in Drug Discovery and Design (1991), Faculty Recognition Award University of Michigan (1992), Outstanding Alumni Achievement Award SUNY Fredonia (1993), MacArthur Foundation Fellowship (1995).  He was elected Senior Fellow in the Michigan Society of Fellows and elected to the SUNY Honor Role (1996), to the Institute of Medicine (1999), American Academy of Arts and Sciences and American Association for the Advancement of Science (2001), and National Academy of Sciences (2006).  He was awarded the Distinguished Faculty Lectureship Award in Biomedical Research by the University of Michigan Medical School (2000) and Michigan Scientist of the Year (2000) by the Impression 5 Science Museum.  Also in 2000 he was a Lecture Platform Speaker at the Chautauqua Institution and selected for Distinguished Faculty Achievement Award at the University of Michigan.  In 2004 he was the recipient the Harrison Howe Award of the American Chemical Society.  In 2007 he received the Repligen Award given by the Biological Chemistry Division of the American Chemical Society and the Kaiser Award from the Protein Society and the Esselen Award for Chemistry in the Public Interest given the Northeastern Section of the American Chemical Society. In 2008 he will be awarded the Murray Goodman Memorial Prize. 

He is a member of the American Chemical Society and the American Society for Biochemistry and Molecular Biology. He currently serves on the Board of Editors of ACS Chemical Biology and on the editorial board of PNAS as well as a number of other journals.  He is a consultant for a number of pharmaceutical companies and has served on the scientific advisory boards of NitroMed, Inc. and Oxon Medica, Inc.  He is a co-founder of Omniox, Inc. He is a member of the Fredonia College Foundation Board of Directors.  In 2008 he was appointed to the HHMI Science Advisory Board.

Marletta's primary research interests lie at the interface of chemistry and biology with emphasis on the study of protein function and enzyme reaction mechanisms. Marletta has made fundamental discoveries concerning the biological action of nitric oxide.  His studies have provided the basis for understanding at the molecular level of this unique cell signaling pathway and the function of nitric oxide in the immune system.  He has uncovered several novel structure/function relationships in nitric oxide synthase and guanylate cyclase. His continued studies on NO signaling have recent led to a molecular understanding of general gas sensing mechanisms in biology. 

Marletta lives with his wife Margaret Gutowski and son Matthew in Berkeley, California. 


Page modified 11/26/14